52 is a critical code and if the ECU is actively seeing the fault the ECU will go in to what is commonly known as "limp mode".... the ECU dumps in tons of extra fuel and pulls very large amounts of spark advance very effectively neutering your engine of any balls it once had.
The transmission problem is very likely due to the inoperable speedometer. The speedometer is where the speed signal for the transmission is generated.
Fixing the speedometer and the knock sensor and/or its wiring may be the sum of what's needed to restore power and driveability.
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